• 研究業績



  • Hoshina T, Fukumoto S, Aonuma H, Saiki E, Hori S, Kanuka H. “Seroprevalence of Toxoplasma gondii in wild sika deer in Japan.”
    Parasitol Int. 71:76-79 (2019)
  • Sombié A, Saiki E, Yaméogo F, Sakurai T, Shirozu T, Fukumoto S, Sanon A, Weetman D, McCall PJ, Kanuka H, Badolo A. “High frequencies of F1534C and V1016I kdr mutations and association with pyrethroid resistance in Aedes aegypti from Somgandé (Ouagadougou), Burkina Faso.”
    Trop Med Health 47: 2 (2019)
  • Endo Y, Onodera A, Obata-Ninomiya K, Koyama-Nasu R, Asou HK, Ito T, Yamamoto T, Kanno T, Nakajima T, Ishiwata K, Kanuka H, Tumes DJ & Nakayama T. “ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis.”
    Nature Metabolism 1: 261–275(2019)
  • Obata-Ninomiya K, Ishiwata K, Nakano H, Endo Y, Ichikawa T, Onodera A, Hirahara K, Okamoto Y, Kanuka H, Nakayama T. “CXCR6+ST2+ memory T helper 2 cells induced the expression of major basic protein in eosinophils to reduce the fecundity of helminth.”
    Proc Natl Acad Sci U S A 115(42): E9849-E9858 (2018)
  • Tabakawa Y, Ohta T, Yoshikawa S, Robinson EJ, Yamaji K, Ishiwata K, Kawano Y, Miyake K, Yamanishi Y, Ohtsu H, Adachi T, Watanabe N, Kanuka H, Karasuyama H. “Histamine released from skin-infiltrating basophils but not mast cells is crucial for acquired tick resistance in mice.”
    Front Immunol 9: 1540 (2018).
  • Ote M, Kanuka H. “A highly secure method for rearing Aedes aegypti mosquitoes.”
    Trop. Med. Health 46: 16 (2018)
  • Yamaji K, Aonuma H, Kanuka H. “Distribution of tick-borne diseases in Japan: Past patterns and implications for the future.”
    J Infect Chemother 24(7): 499-504 (2018)
  • Ishii M, Kanuka H, Badolo A, Sagnon N, Guelbeogo WM, Koike M, Aiuchi D. “Proboscis infection route of Beauveria bassiana triggers early death of Anopheles mosquito.”
    Sci Rep 7 (1): 347 (2017)
  • Badolo A, Bando H, Traoré A, Ko-Ketsu M, Guelbeogo WM, Kanuka H, Ranson H, Sagnon N, Fukumoto S. “Detection of G119S ace-1 (R) mutation in field-collected Anopheles gambiae mosquitoes using allele-specific loop-mediated isothermal amplification (AS-LAMP) method.”
    Malaria J 14: 477 (2015)
  • Tsubokawa D, Ishiwata K, Goso Y, Yokoyama T, Kanuka H, Ishihara K, Nakamura T, Tsuji N. “Induction of Sd(a)-sialomucin and sulfated H-sulfomucin in mouse small intestinal mucosa by infection with parasitic helminth.”
    Exp Parasitol 153: 165-173 (2015)
  • Yoshimura A, Koketsu M, Bando H, Saiki E, Suzuki M, Watanabe Y, Kanuka H, Fukumoto S. “Phylogenetic comparison of avian haemosporidian parasites from resident and migratory birds in northern Japan.”
    J Wildl Dis 50(2): 235-242 (2014)
  • Nei Y, Obata-Ninomiya K, Tsutsui H, Ishiwata K, Miyasaka M, Matsumoto K, Nakae S, Kanuka H, Inase N, Karasuyama H. “GATA-1 regulates the generation and function of basophils.”
    Proc Natl Acad Sci U S A 110(46): 18620-18625 (2013)
  • Obata-Ninomiya K, Ishiwata K, Tsutsui H, Nei Y, Yoshikawa S, Kawano Y, Minegishi Y, Ohta N, Watanabe N, Kanuka H, Karasuyama H. “The skin is an important bulwark of acquired immunity against intestinal helminths.”
    J Exp Med 210(12): 2583-2595 (2013)
  • Aonuma H, Badolo A, Okado K, Kanuka H. “Detection of mutation by allele-specific loop-mediated isothermal amplification (AS-LAMP).”
    Methods Mol Biol 1039: 121-127 (2013)
  • Bando H, Okado K, Guelbeogo WM, Badolo A, Aonuma H, Nelson B, Fukumoto S, Xuan X, Sagnon N, Kanuka H. “Intra-specific diversity of Serratia marcescens in Anopheles mosquito midgut defines Plasmodium transmission capacity.”
    Sci Rep 3: 1641 (2013)
  • Takeishi A, Kuranaga E, Tonoki A, Misaki K, Yonemura S, Kanuka H, Miura M. “Homeostatic epithelial renewal in the gut is required for dampening a fatal systemic wound response in Drosophila.”
    Cell Rep 3(3): 919-930 (2013)
  • Saiki E, Nagao K, Aonuma H, Fukumoto S, Xuan X, Bannai M, Kanuka H. “Multivariable analysis of host amino acids in plasma and liver during infection of malaria parasite Plasmodium yoelii.”
    Malar J 12: 19 (2013)
  • Nelson B, Freisinger T, Ishii K, Okado K, Shinzawa N, Fukumoto S, Kanuka H. “Activation of Imd pathway in hemocyte confers infection resistance through humoral response in Drosophila.”
    Biochem Biophys Res Commun 430(3): 1120-1125 (2013)
  • Badolo A, Okado K, Guelbeogo WM, Aonuma H, Bando H, Fukumoto S, Sagnon N, Kanuka H. “Development of an allele-specific, loop-mediated, isothermal amplification method (AS-LAMP) to detect the L1014F kdr-w mutation in Anopheles gambiae s. l.”
    Malar J 11: 227 (2012)
  • Makioka A, Kumagai M, Hiranuka K, Kobayashi S, Takeuchi T. “Entamoeba invadens: identification of ADF/cofilin and their expression analysis in relation to encystation and excystation.”
    Exp Parasitol 127 (1): 195-201 (2011)
  • Doi Y, Shinzawa N, Fukumoto S, Okano H, Kanuka H. “Calcium signal regulates temperature-dependent transformation of sporozoites in malaria parasite development.”
    Exp Parasitol 128(2): 176-180 (2011)
  • Maekawa E, Aonuma H, Nelson B, Yoshimura A, Tokunaga F, Fukumoto S, Kanuka H. “The role of proboscis of the malaria vector mosquito Anopheles stephensi in host-seeking behavior.”
    Parasit Vectors 4(1): 10 (2011)
  • Kubori T, Shinzawa N, Kanuka H, and Nagai H. “Legionella metaeffector exploits host proteasome to temporally regulate cognate effector.”
    PLoS Pathogens 6(12): e1001216 (2010)
  • Ishiwata K, Watanabe N, Guo M, Tomihara K, Brumlik MJ, Yagita H, Pardoll D, Chen L, Shin T. “Costimulator B7-DC attenuates strong Th2 responses induced by Nippostrongylus brasiliensis.”
    J Immunol 184(4): 2086-2094 (2010)
  • Kumagai M, Inaba T, Makioka A, Ishiwata K, Onishi K, Watanabe N. “An improved glycerin-jelly mounting procedure for permanent preparations of helminth eggs.”
    J Parasitol 96(2): 440-441 (2010)
  • Doi Y, Shinzawa N, Fukumoto S, Okano H, Kanuka H. “ADF2 regulates transformation of the ookinete and sporozoite in malaria parasite development.”
    Biochem Biophys Res Commun 397(4): 668-672 (2010)
  • Aonuma H, Yoshimura A, Kobayashi T, Okado K, Badolo A, Nelson B, Kanuka H, Fukumoto S. “A single fluorescence-based LAMP reaction for identifying multiple parasites in mosquitoes.”
    Exp Parasitol 125(2): 179-183 (2010)
  • Shinzawa N, Nelson B, Aonuma H, Okado K, Fukumoto S, Miura M, Kanuka H. “p38 MAPK-dependent phagocytic encapsulation confers infection tolerance in Drosophila.”
    Cell Host Microbe 6(3): 244-252 (2009) (同誌 Preview にて紹介)
  • Aonuma H, Yoshimura A, Perera N, Shinzawa N, Bando H, Oshiro S, Nelson B, Fukumoto S, Kanuka H. “Loop-mediated isothermal amplification applied to filarial parasites detection in the mosquito vectors: Dirofilaria immitis as a study model.”
    Parasit Vectors 2(1): 15 (2009)
  • Okado K, Shinzawa N, Aonuma H, Nelson B, Fukumoto S, Fujisaki K, Kawazu S, Kanuka H. “Rapid recruitment of innate immunity regulates variation of intracellular pathogen resistance in Drosophila.”
    Biochem Biophys Res Commun 379(1): 6-10 (2009)
  • Perera N, Aonuma H, Yoshimura A, Teramoto T, Iseki H, Nelson B, Igarashi I, Yagi T, Fukumoto S, Kanuka H. “Rapid identification of virus-carrying mosquitoes using reverse transcription-loop-mediated isothermal amplification.”
    J Virol Methods 156(1-2): 32-36 (2009)
  • Aonuma H, Suzuki M, Iseki H, Perera N, Nelson B, Igarashi I, Yagi T, Kanuka H, Fukumoto S. “Rapid identification of Plasmodium-carrying mosquitoes using loop-mediated isothermal amplification.”
    Biochem Biophys Res Commun 376(4): 671-676 (2008).
  • Kuranaga E, Kanuka H, Tonoki A, Takemoto K, Tomioka T, Kobayashi M, Hayashi S, Miura M. “Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs.”
    Cell 126(3): 583-596 (2006)
  • Kanuka H, Kuranaga E, Takemoto K, Hiratou T, Okano H, Miura M. “Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development.”
    EMBO J 24(21): 3793-3806 (2005)
  • Kumagai M, Makioka A, Takeuchi T, Nozaki T. “Molecular cloning and characterization of a protein farnesyltransferase from the enteric protozoan parasite Entamoeba histolytica.”
    J Biol Chem 279, 2316-2323 (2004)


  • 嘉糠洋陸「エボラ出血熱・SFTS・デング熱─感染症はどこから現れ,どこへ行くのか」
    実験医学 33: 72-78 (2015)
  • 青沼宏佳「バンパイアが運ぶ感染症:病原体媒介節足動物のいま」
    実験医学 31: 3066-3071 (2013)
  • 横山卓也、青沼宏佳、嘉糠洋陸「病原体を運ぶ蚊の免疫システム」
    化学と生物 50: 196-202 (2012)
  • 新澤直明、嘉糠洋陸「感染に対する宿主側トレランス機構の発見」
    生化学 82(11): 1051-1055 (2010)
  • 新澤直明、嘉糠洋陸「貪食性囲い込みは細菌感染に対するトレランスを制御する」
    細胞工学 28: 1278-1279 (2009)
  • 新澤直明、嘉糠洋陸「ショウジョウバエを用いたヒト疾患分子基盤の解明-光るハエは医学へ貢献できるか」
    医学のあゆみ 230: 129-133 (2009)
  • 新澤直明、嘉糠洋陸「宿主−病原体相互作用解明に向けたショウジョウバエ感染症モデル」
    薬学雑誌 126: 1219-1226 (2006)
  • 嘉糠洋陸「“マラリア非媒介蚊は”盛者必衰”への切り札となるか」
    細胞工学 25: 528-532 (2006)
  • 青沼宏佳、嘉糠洋陸「寄生虫に対する貪食—“似て非なる者”の認識メカニズム」
    蛋白質核酸酵素 51: 131-137 (2006)
  • 青木克己、北潔、嘉糠洋陸「分子寄生虫学入門—分子的アプローチが紐解く生命現象」
    細胞工学 24: 1100-1104 (2005)